TP53BP1 anticorps (C-Term)

N° du produit ABIN7464819

Cet anticorps Lapin Polyclonal détecte spécifiquement TP53BP1 dans WB, IHC, IF, ICC et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour TP53BP1 anticorps (C-Term) (ABIN7464819)

Antigène: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TP53BP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: KO Validated

Détail du produit anti-TP53BP1 anticorps

Épitope: C-Term

Réactivité croisée: Humain, Souris

Purification: Purified by antigen-affinity chromatography.

Immunogène: Synthetic peptide corresponding to the carboxy-terminus of h53BP1, conjugated to a carrier protein.

Isotype: IgG

Information d'application

Indications d'application: Suggested starting dilutions are as follows: WB: 1:500-1:3000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Commentaires:

Positive Control: Neuro 2A , C8D30 , NIH-3T3 , HeLa

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.83 mg/mL

Buffer: PBS, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TP53BP1

Antigène: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Autre désignation: tumor protein p53 binding protein 1

Sujet: Tumor protein p53 binding protein 1 , 53BP1 , TDRD30 , p202 , p53BP1,P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

Poids moléculaire: 214 kDa

ID gène: 7158

UniProt: Q12888

Pathways: Réparation de l'ADN